Cytotoxic and Micronuclei Inducing Effects of Petroleum Ether Fraction of Leaf Aqueous Extract of <i>Clerodendrum viscosum</i> Vent. in <i>Allium cepa</i> Root Tip Cells

Clerodendrum viscosum is a traditionally used medicinal plant. The present study aimed to analyze detailed cytotoxic effect of the non-polar petroleum ether fraction (AQPEF) leaf aqueous extract C. Vent. (LAECV) in Allium cepa root tip cells. LAECV was fractionated with and tested for A. toxicity. Micronuclei, polyploidy, mitotic abnormalities were analyzed after AQPEF treatment. induced concentration-dependent increased abnormalities, micronuclei, polyploid cell frequency cells that comparable colchicine effects. Thus, explores suitable solvent extraction active phytochemicals LAECV; having like polyploidy abnormality inducing potentials cells, indicating its perspective use karyotyping, plant breeding programs, cytotoxicity studies.